H-pyrazolo[1,5-a]pyridine-2-carboxylic acid

H-pyrazolo[1,5-a]pyridine-2-carboxylic acid - Names and Identifiers

Name	Pyrazolo[1,5-a]pyridine-2-carboxylic acid
Synonyms	pyrazolo[1,5-a]pyridine-2-carb Pyraxolo[1,5-a]pyridine-2-carboxylicacid PYRAZOLO[1,5-A]PYRIDINE-2-CARBOXYLIC ACID Pyrazolo[1,5-a]pyridine-2-carboxylic acid H-pyrazolo[1,5-a]pyridine-2-carboxylic acid 5-HYDROXYINDOLINE-2-CARBOXYLIC ACID ETHYL ESTER Pyrazolo[1,5-a]pyridine-2-carboxylic acid, tech
CAS	63237-88-7
InChI	InChI=1/C8H6N2O2/c11-8(12)7-5-6-3-1-2-4-10(6)9-7/h1-5H,(H,11,12)

H-pyrazolo[1,5-a]pyridine-2-carboxylic acid - Physico-chemical Properties

Molecular Formula	C8H6N2O2
Molar Mass	162.15
Density	1.41±0.1 g/cm3(Predicted)
Melting Point	189 °C
pKa	-3.82±0.41(Predicted)
Storage Condition	2-8°C
Refractive Index	1.676

H-pyrazolo[1,5-a]pyridine-2-carboxylic acid - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard Note	Harmful

H-pyrazolo[1,5-a]pyridine-2-carboxylic acid - Introduction

Pyrazolo[1,5-a]pyridine-2-carboxylic acid(Pyrazolo[1,5-a]pyridine-2-carboxylic acid) is an organic compound whose chemical formula is C8H5N3O2. Here are some information about its nature, use, formulation and safety:

Nature:
-Appearance: Pyrazolo[1,5-a]pyridine-2-carboxylic acid is white to light yellow crystalline powder.
-Solubility: It has good solubility in some organic solvents (such as chloroform, dimethylformamide).
-melting point: about 156-158 ℃.
-Stability: It is relatively stable at room temperature.

Use:
- Pyrazolo[1,5-a]pyridine-2-carboxylic acid can be used as an intermediate in organic synthesis and has a wide range of applications, such as drug synthesis, pesticide synthesis, etc.
-It also has potential antiviral and anticancer activities in the field of medicine, so it has been widely studied.

Preparation Method:
Pyrazolo[1,5-a]pyridine-2-carboxylic acid is generally prepared by organic synthesis methods. Common preparation methods include:
1. Synthesis by cyclization reaction of pyridine and ketone compounds.
2. Synthesized by the reaction of pyrazole with 2-cyanopyridine.

Safety Information:
- Pyrazolo[1,5-a]pyridine-2-carboxylic acid is relatively safe under correct operation, but the following matters still need to be paid attention:
-This compound has low toxicity and irritation, but it is still necessary to follow laboratory safety procedures during operation.
-During operation, personal protective equipment such as protective glasses and laboratory gloves should be worn to avoid direct contact with skin or eyes.
-Try to avoid inhalation or ingestion of the compound. In case of accidental inhalation or ingestion, seek medical attention and take the compound's safety data to the hospital for emergency treatment.
-During storage, avoid contact with oxidants or combustibles, and store in a dry, cool place.
-In case of leakage or accident, take appropriate measures to clean up immediately and deal with it in accordance with local regulations.

Last Update：2024-04-09 02:00:47